Collagen cross linking: Current perspectives

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collagen cross-linking

patients with keratoconus constitute a large proportion of patients suffering from anterior segment disorders. as of this time, however, its pathogenesis has not yet been elucidated. a reduction in cross-link between collagen molecules has been observed in keratoconic eyes as compared to normal ones. present approaches only address refractive errors resulting from the abnormal abnormal corneal ...

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Collagen Cross-Linking: Current Status and Future Directions

Collagen cross-linking (CXL) using UVA light and riboflavin (vitamin B2) was introduced as a clinical application to stabilize the cornea by inducing cross-links within and between collagen fibers. CXL has been investigated extensively and has been shown clinically to arrest the progression of keratoconic or post-LASIK ectasia. With its minimal cost, simplicity, and proven positive clinical out...

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Corneal collagen cross-linking procedures

Objective: to present corneal collagen corsslinking techniques. Corneal collagen cross-linking (CXL) is a procedure used to slow down or arrest the progression of keratoconus in order to avoid or, at least delay the necessity of keratoplasty. CXL means photopolimerisation of the stromal fibrillar tissue, in order to increase their stiffness and resistance to the corneal ectasia. CXL is a proces...

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Corneal Collagen Cross Linking - PLUS

The management of keratoconus and post – LASIK ectasia included until recently spectacle correction, Hard Fitted Gas Permeable Contact Lenses, Intrastromal Corneal Ring Segments. All these interventions are purely symptomatic and their only aim is the improvement of visual function of patients, without interfering with the pathophysiology of the ectatic disorders. The only actual treatment for ...

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Standard versus trans-epithelial collagen cross-linking in keratoconus patients suitable for standard collagen cross-linking

PURPOSE Evaluating the clinical results of trans-epithelial collagen cross-linking (CXL) and standard CXL in patients with progressive keratoconus. METHODS This prospective study comprised 20 eyes of 20 patients with progressive keratoconus. Ten eyes were treated by standard CXL and ten by trans-epithelial cross-linking (TE-CXL, epithelium on) with 1 year of follow-up. All patients underwent ...

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ژورنال

عنوان ژورنال: Indian Journal of Ophthalmology

سال: 2013

ISSN: 0301-4738

DOI: 10.4103/0301-4738.116071